PTGER3 and RGS17

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PTGER3	RGS17
Description		prostaglandin E receptor 3	regulator of G protein signaling 17
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GO Annotations	Cellular Component	Cell Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Plasma Membrane Cell Junction Neuron Projection Synapse
	Molecular Function	Prostaglandin E Receptor Activity	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Prostanoid ligand receptors G alpha (i) signalling events	G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs		Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)	Alcohol dependence ( 26365420) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) General risk tolerance (MTAG) ( 30643258) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	18 interacting genes: ADRB2 AQP1 DHX37 GNAI1 GNAI3 HOXA1 LCE2A LCE3C LCE4A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SMCP TBC1D16
Entrez ID		5733	26575
HPRD ID		08906	06223
Ensembl ID		ENSG00000050628	ENSG00000091844
Uniprot IDs		O00325 P43115	Q9UGC6
PDB IDs		6AK3 6M9T	1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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