PAK5 and CRBN

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 381
  • Data Source:
  • BioGRID (two hybrid)

PAK5

CRBN

Description p21 (RAC1) activated kinase 5 cereblon
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Atopy ( 28927820)
  • Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Basophil percentage of granulocytes ( 27863252)
  • Basophil percentage of white cells ( 27863252)
  • Immune response to smallpox vaccine (IL-6) ( 22542470)
  • Knee osteoarthritis ( 27696742)
  • Restless legs syndrome ( 29029846)
  • White blood cell count (basophil) ( 29403010 27863252)
  • White matter integrity ( 23218918)
Interacting Genes 21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT 33 interacting genes: APPL2 BCL6 BCL6B BSG CSNK1A1 EGR1 EGR4 GLUL GRB2 GSPT1 GZF1 HIC1 HIC2 IKZF3 KDM1A OSR1 OSR2 PAK5 PIK3R3 RBPMS RBX1 SALL1 SALL3 SALL4 SLC16A1 SQSTM1 SUV39H1 TP53 UBE2D1 WIZ ZBTB7A ZBTB7B ZFP91
Entrez ID 57144 51185
HPRD ID 06423 16750
Ensembl ID ENSG00000101349 ENSG00000113851
Uniprot IDs B0AZM9 Q9P286 Q96SW2
PDB IDs 2F57 4M91 4TZ4 5FQD 5HXB 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6H0F 6H0G
Enriched GO Terms of Interacting Partners?
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