PRPH and LMNB1

Number of citations of the paper that reports this interaction (PubMedID 1986862)
21

Data Source:
HPRD (in vitro)

		PRPH	LMNB1
Description		peripherin	lamin B1
Image		No pdb structure
GO Annotations	Cellular Component	Intermediate Filament Membrane Type III Intermediate Filament Extracellular Exosome	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intermediate Filament Cytoskeleton Organization	Interleukin-12-mediated Signaling Pathway
Pathways			Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)	Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)
Interacting Genes		5 interacting genes: KRT15 LMNB1 MYO5A PRPH2 VIM	29 interacting genes: ABCG8 ATF4 CASP3 CASP6 CDK1 GABARAP GIT2 GZMA GZMB LBR LMNA MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PLEC PRKCA PRKCB PRKCD PRPH RNF123 SERPINA3 SRPK2 SUMO4 TMPO TOR1AIP1 URB2 YWHAQ
Entrez ID		5630	4001
HPRD ID		01365	01036
Ensembl ID		ENSG00000135406	ENSG00000113368
Uniprot IDs		B3KWQ6 P41219	B4DZT3 P20700
PDB IDs			2KPW 3JT0 3TYY 3UMN 5VVX
Enriched GO Terms of Interacting Partners?
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