LMNB1 and MAP1LC3C

Number of citations of the paper that reports this interaction (PubMedID 26524528)
109

Data Source:
BioGRID (pull down)

		LMNB1	MAP1LC3C
Description		lamin B1	microtubule associated protein 1 light chain 3 gamma
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding
	Biological Process	Interleukin-12-mediated Signaling Pathway	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation
Pathways		Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Macroautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)	Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: ABCG8 ATF4 CASP3 CASP6 CDK1 GABARAP GIT2 GZMA GZMB LBR LMNA MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PLEC PRKCA PRKCB PRKCD PRPH RNF123 SERPINA3 SRPK2 SUMO4 TMPO TOR1AIP1 URB2 YWHAQ	19 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATG4B CUL3 KBTBD6 KBTBD7 LMNB1 MEFV NEDD4 OPTN RB1CC1 SQSTM1 TAX1BP1 TRIM21 ULK1 WDFY3 WDR81
Entrez ID		4001	440738
HPRD ID		01036	14226
Ensembl ID		ENSG00000113368	ENSG00000197769
Uniprot IDs		B4DZT3 P20700	Q9BXW4
PDB IDs		2KPW 3JT0 3TYY 3UMN 5VVX	2NCN 3VVW 3WAM 3WAP 5DPW
Enriched GO Terms of Interacting Partners?
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