LMNB1 and TMPO

Number of citations of the paper that reports this interaction (PubMedID 9490046)
7

Data Source:
HPRD (in vitro, two hybrid)

		LMNB1	TMPO
Description		lamin B1	thymopoietin
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane	Chromatin Nucleus Nuclear Envelope
	Molecular Function	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding Lamin Binding Cadherin Binding
	Biological Process	Interleukin-12-mediated Signaling Pathway	Regulation Of Transcription, DNA-templated
Pathways		Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)	Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: ABCG8 ATF4 CASP3 CASP6 CDK1 GABARAP GIT2 GZMA GZMB LBR LMNA MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PLEC PRKCA PRKCB PRKCD PRPH RNF123 SERPINA3 SRPK2 SUMO4 TMPO TOR1AIP1 URB2 YWHAQ	19 interacting genes: ABL1 AKAP8L BANF1 CLK1 CSNK2A1 GMCL1 HDAC3 LMNA LMNB1 LMNB2 OIP5 RB1 RNF123 SGTA SGTB SRC SRPK2 SUMO2 USP7
Entrez ID		4001	7112
HPRD ID		01036	01777
Ensembl ID		ENSG00000113368	ENSG00000120802
Uniprot IDs		B4DZT3 P20700	A0A024RBE7 A0A024RBH7 G5E972 P42166 P42167 Q59G12
PDB IDs		2KPW 3JT0 3TYY 3UMN 5VVX	1GJJ 1H9E 1H9F
Enriched GO Terms of Interacting Partners?
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