LMNB1 and PRPH

Number of citations of the paper that reports this interaction (PubMedID 1986862)
21

Data Source:
HPRD (in vitro)

		LMNB1	PRPH
Description		lamin B1	peripherin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Lamin Filament Nucleoplasm Membrane Nuclear Matrix Nuclear Membrane	Intermediate Filament Membrane Type III Intermediate Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding Phospholipase Binding Sequence-specific Double-stranded DNA Binding	Structural Molecule Activity Protein Binding
	Biological Process	Interleukin-12-mediated Signaling Pathway	Intermediate Filament Cytoskeleton Organization
Pathways		Meiotic synapsis Formation of Senescence-Associated Heterochromatin Foci (SAHF) Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Breakdown of the nuclear lamina Depolymerisation of the Nuclear Lamina Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases			Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Blood protein levels ( 30072576 29875488) Body fat percentage ( 31752434) Parkinson's disease (motor and cognition) ( 22658654)	Prostate cancer ( 21743467) Sural nerve amplitude potential ( 30992453)
Interacting Genes		29 interacting genes: ABCG8 ATF4 CASP3 CASP6 CDK1 GABARAP GIT2 GZMA GZMB LBR LMNA MAP1LC3A MAP1LC3C MBIP MELK PIAS2 PLEC PRKCA PRKCB PRKCD PRPH RNF123 SERPINA3 SRPK2 SUMO4 TMPO TOR1AIP1 URB2 YWHAQ	5 interacting genes: KRT15 LMNB1 MYO5A PRPH2 VIM
Entrez ID		4001	5630
HPRD ID		01036	01365
Ensembl ID		ENSG00000113368	ENSG00000135406
Uniprot IDs		B4DZT3 P20700	B3KWQ6 P41219
PDB IDs		2KPW 3JT0 3TYY 3UMN 5VVX
Enriched GO Terms of Interacting Partners?
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