EIF2AK2 and JAK1

  • Number of citations of the paper that reports this interaction (PubMedID 17290288)
  • 14
  • Data Source:
  • HPRD (in vivo)

EIF2AK2

JAK1

Description eukaryotic translation initiation factor 2 alpha kinase 2 Janus kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Glucose homeostasis traits ( 25524916)
  • Core binding factor acute myeloid leukemia ( 27903959)
  • Eosinophil counts ( 27863252)
  • Eosinophil percentage of granulocytes ( 27863252)
  • Eosinophil percentage of white cells ( 27863252)
  • Medication use (thyroid preparations) ( 31015401)
  • Multiple sclerosis ( 31604244)
  • Neutrophil percentage of granulocytes ( 27863252)
  • Plasma anti-thyroglobulin levels ( 29678681)
  • Sum eosinophil basophil counts ( 27863252)
Interacting Genes 49 interacting genes: CASP3 CASP7 CASP8 CDC42 CHUK DHX30 DHX58 DHX9 DICER1 DNAJC3 EDC4 EIF2S1 EIF6 ELF2 FTSJ3 H2AC20 H2AC4 HSP90AA1 HSPA1A IKBKB IL7R ILF2 ILF3 JAK1 MAP3K5 MAP3K7 METAP2 MOV10 NFKBIA NPM1 PDGFRB PPP1CA PPP1CC PPP2R5A PRKRA PRKRIP1 PTGES3 RAC1 STAT1 STAT3 STRBP TAB2 TARBP2 THAP12 TIRAP TOLLIP TP53 TYK2 ZNF346 71 interacting genes: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GAB1 GHR GRB2 H3-4 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RACK1 RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2 USP6
Entrez ID 5610 3716
HPRD ID 01468 00992
Ensembl ID ENSG00000055332 ENSG00000162434
Uniprot IDs P19525 Q8IW76 P23458 Q6P669
PDB IDs 1QU6 2A19 2A1A 3UIU 6D3K 6D3L 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01 5E1E 5HX8 5IXD 5IXI 5KHW 5KHX 5L04 5WO4 6AAH 6BBU 6C7Y 6DBN 6ELR 6GGH 6HZU 6N77 6N78 6N79 6N7A 6N7B 6N7C 6N7D
Enriched GO Terms of Interacting Partners?
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