MAP2K6 and MAPK12

  • Number of citations of the paper that reports this interaction (PubMedID 11062067)
  • 49
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

MAP2K6

MAPK12

Description mitogen-activated protein kinase kinase 6 mitogen-activated protein kinase 12
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Optic disc size ( 31809533)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
  • Waist-hip ratio ( 28552196)
Interacting Genes 37 interacting genes: AKT1 BECN1 BRAF CCND2 CDKN2B DCTN1 EPHA2 FBXO7 FGFR4 GLIS2 HGF HRAS LRRK2 MAP2K3 MAP2K4 MAP2K5 MAP3K20 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 PKN1 PLCB2 RAF1 RASSF1 RELA SMAD7 STAT4 STK11 TAOK2 TLR3 TRAF6 28 interacting genes: DLG1 DLG2 DLG3 DLG4 DUSP1 EEF2K ERBIN GRB2 GTF2I HTRA2 MAP2K3 MAP2K4 MAP2K6 MAPKAPK5 MAPT MBP PATJ PKN1 PTPN3 PTPN4 RCSD1 RGS3 SH3BP5 SIAH1 SNTA1 SNTB1 SRPK1 TERF1
Entrez ID 5608 6300
HPRD ID 03155 03868
Ensembl ID ENSG00000108984 ENSG00000188130
Uniprot IDs A0A024R8K3 A8K3Y2 P52564 P53778 Q6N076
PDB IDs 2Y8O 3ENM 3FME 3VN9 5ETF 1CM8 4QUM
Enriched GO Terms of Interacting Partners?
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