MAP2K6 and MAP3K4

  • Number of citations of the paper that reports this interaction (PubMedID 9841871)
  • 17
  • Data Source:
  • BioGRID (imaging technique)
  • HPRD (in vivo, in vitro)

MAP2K6

MAP3K4

Description mitogen-activated protein kinase kinase 6 mitogen-activated protein kinase kinase kinase 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Optic disc size ( 31809533)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
  • Waist-hip ratio ( 28552196)
  • Aging ( 22773346)
  • Blood protein levels ( 28240269)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Lipoprotein (a) levels ( 26377243)
  • Ovarian disease with few adhesions ( 28333195)
Interacting Genes 37 interacting genes: AKT1 BECN1 BRAF CCND2 CDKN2B DCTN1 EPHA2 FBXO7 FGFR4 GLIS2 HGF HRAS LRRK2 MAP2K3 MAP2K4 MAP2K5 MAP3K20 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 PKN1 PLCB2 RAF1 RASSF1 RELA SMAD7 STAT4 STK11 TAOK2 TLR3 TRAF6 26 interacting genes: ANXA2 AXIN1 BUB1B CDC42 CHUK CNTRL DIXDC1 GADD45A GADD45B GADD45G GSK3B MAP2K1 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPK13 MFHAS1 PTK2B PTPN11 RAC1 RACGAP1 RUNX2 TPR TRAF4 YWHAZ
Entrez ID 5608 4216
HPRD ID 03155 03886
Ensembl ID ENSG00000108984 ENSG00000085511
Uniprot IDs A0A024R8K3 A8K3Y2 P52564 Q9P1M2 Q9Y6R4
PDB IDs 2Y8O 3ENM 3FME 3VN9 5ETF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?