XPA and ATM

  • Number of citations of the paper that reports this interaction (PubMedID 16540648)
  • 40
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

XPA

ATM

Description XPA, DNA damage recognition and repair factor ATM serine/threonine kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hypothyroidism ( 27182965)
  • Obesity-related traits ( 23251661)
  • Serum thyroid-stimulating hormone levels ( 24852370)
  • Thyroid cancer (Papillary, radiation-related) ( 20350937)
Interacting Genes 25 interacting genes: AP2M1 ATM ATR DDB1 DDB2 ERCC1 ERCC4 ERCC6 GPN1 GTF2E2 GTF2H1 HERC2 MSH2 MSH3 NDEL1 PCNA PRKDC RASSF1 RHOU RPA1 RPA2 RPA4 TRIM27 XAB2 XPC 97 interacting genes: AATF ABL1 ACTL6B AP1B1 AP2B1 AP3B1 AP3B2 ATR BCAS3 BCL10 BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 COPS5 CREB1 CRX CSNK1D CXXC5 DAXX DCAF1 DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 ERRFI1 EXO1 FANCD2 FECH FOXO3 H2AX HIF1A HSPA8 IL24 KAT5 KAT8 LIG4 MAP1S MCM2 MCPH1 MDC1 MDM2 MDM4 MRE11 MT-ND4 MTA3 NBN NR4A1 NREP NSD3 OSGIN1 PARP1 PEX5 POLR2A PPP2R5C PRKDC PTCH1 RAD17 RAD51 RAD9A RANBP9 RASSF1 RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TFF1 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 TRIM29 UCHL3 WRN XPA XRCC5 ZEB1 ZNF821
Entrez ID 7507 472
HPRD ID 02045 06347
Ensembl ID ENSG00000136936 ENSG00000149311
Uniprot IDs P23025 A0A024R3C7 Q13315
PDB IDs 1D4U 1XPA 2JNW 6J44 6RO4 5NP0 5NP1 6HKA
Enriched GO Terms of Interacting Partners?
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