RNF126 and OTUB2

Number of citations of the paper that reports this interaction (PubMedID 23105109)
16

Data Source:
BioGRID (two hybrid)

		RNF126	OTUB2
Description		ring finger protein 126	OTU deubiquitinase, ubiquitin aldehyde binding 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Protein Ubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Retrograde Transport, Endosome To Golgi Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System	Protein Deubiquitination Protein K11-linked Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Arterial stiffness ( 31070453) Arterial stiffness index ( 31235810) Pulse pressure ( 30578418)
Interacting Genes		34 interacting genes: AICDA BAG6 CDKN1A CSNK2B E2F1 EGFR FXN HMGCL MAP3K1 MDM2 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 RNF168 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBL4A USP15 USP2 XRCC5 XRCC6	35 interacting genes: APP ARRDC3 CPSF6 FAM168A GLI2 KRT31 KRT40 LZTS2 MAGEA11 MID1 MID2 PJA1 RBCK1 REL RFFL RNF126 SIAH1 TP53BP2 TRAF6 TRIM2 TRIM25 TRIM26 TRIM27 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIP6 U2AF2 UBC UBE2N USP21 USP28
Entrez ID		55658	78990
HPRD ID		11501	07620
Ensembl ID		ENSG00000070423	ENSG00000089723
Uniprot IDs		A0A024R206 A8K0Q1 Q9BV68	Q96DC9
PDB IDs		2N9O 2N9P	1TFF 4FJV
Enriched GO Terms of Interacting Partners?
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