FAM90A1 and STX11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FAM90A1	STX11
Description		family with sequence similarity 90 member A1	syntaxin 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process		Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Gut microbiota (functional units) ( 27694959)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		38 interacting genes: APP BANP CALCOCO2 CCDC57 CEP55 CEP72 CEP76 COG6 DVL2 EXOSC8 FHL3 FSD2 FXR2 GABPB1 GNPTAB GOLGA2 GOPC KASH5 KRT31 KRT38 KRT40 LDOC1 LRRK2 MID2 MTUS2 PSME3 PSTPIP1 RINT1 SIAH1 SRPK2 STAC3 STX11 TMCC2 TRAF2 TRAF4 TRIM23 ZBTB14 ZNF212	64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587
Entrez ID		55138	8676
HPRD ID		07672	09231
Ensembl ID		ENSG00000171847	ENSG00000135604
Uniprot IDs		Q86YD7	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?
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