ROPN1 and CKS1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ROPN1	CKS1B
Description		rhophilin associated tail protein 1	CDC28 protein kinase regulatory subunit 1B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Motile Cilium	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleoplasm SCF Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
	Biological Process	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium	Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Cell Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division
Pathways		RHO GTPases Activate Rhotekin and Rhophilins	SCF(Skp2)-mediated degradation of p27/p21 Cyclin D associated events in G1
Drugs			Fluoxetine Meta Vanadate
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048)	Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732)
Interacting Genes		26 interacting genes: AKAP3 AKAP7 CEP57L1 CKS1B CNST FAM162A GNL3L GPKOW HNRNPUL1 KIF9 LENG1 LNX1 LNX2 NTAQ1 POLR3C PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SPA17 TSNAXIP1 TULP3 UBE2W XKR3	32 interacting genes: AP2M1 ARID5A CBY2 CCNA1 CCNB2 CDC27 CDC37 CDK2 CDKN1B CDX4 CKS1BP7 CKS2 CUL1 DUSP1 ECPAS HSP90AA1 IKZF1 KRTAP10-9 KRTAP5-9 LDHB MEOX1 MIPOL1 PSMD9 REL ROPN1 SEPTIN3 SKP2 SSBP1 SUMO1P1 TCF4 TRIM27 XIAP
Entrez ID		54763	1163
HPRD ID		15269	00299
Ensembl ID		ENSG00000065371	ENSG00000173207
Uniprot IDs		A0A140VKB2 Q9HAT0	P61024 Q5T178
PDB IDs			1BUH 1DKS 1DKT 2ASS 2AST 4YC6
Enriched GO Terms of Interacting Partners?
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