ROPN1 and UBE2W

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ROPN1	UBE2W
Description		rhophilin associated tail protein 1	ubiquitin conjugating enzyme E2 W
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Motile Cilium	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium	Protein Polyubiquitination DNA Repair Protein Monoubiquitination Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Response To Misfolded Protein
Pathways		RHO GTPases Activate Rhotekin and Rhophilins	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048)	Manganese levels ( 26025379) Urate levels in obese individuals ( 25811787)
Interacting Genes		26 interacting genes: AKAP3 AKAP7 CEP57L1 CKS1B CNST FAM162A GNL3L GPKOW HNRNPUL1 KIF9 LENG1 LNX1 LNX2 NTAQ1 POLR3C PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SPA17 TSNAXIP1 TULP3 UBE2W XKR3	75 interacting genes: AKR1C3 AMFR BARD1 BFAR BIRC2 BIRC8 BRCA1 CADPS2 CBL CHFR CNOT4 DNMT3B DTX3 DTX3L DZIP3 EED ELOC FANCL LRSAM1 MAP3K1 MARCHF3 MARCHF5 MGRN1 MIB1 MID1 MKRN1 MKRN3 MUL1 PJA2 POLR2C PSTPIP1 RFWD3 RMND5B RNF10 RNF103 RNF111 RNF114 RNF115 RNF123 RNF125 RNF138 RNF14 RNF150 RNF152 RNF165 RNF166 RNF167 RNF185 RNF2 RNF26 RNF31 RNF4 RNF5 RNF8 ROPN1 STUB1 TOPORS TRIM17 TRIM2 TRIM21 TRIM23 TRIM27 TRIM31 TRIM35 TRIM39 TRIM5 TRIM8 UBA1 UBOX5 UFM1 UHRF2 USHBP1 XIAP ZNRF1 ZNRF4
Entrez ID		54763	55284
HPRD ID		15269	07724
Ensembl ID		ENSG00000065371	ENSG00000104343
Uniprot IDs		A0A140VKB2 Q9HAT0	Q96B02 Q96FI0 X6REH9
PDB IDs			2A7L 2MT6
Enriched GO Terms of Interacting Partners?
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