CKS1B and CDX4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CKS1B	CDX4
Description		CDC28 protein kinase regulatory subunit 1B	caudal type homeobox 4
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleoplasm SCF Ubiquitin Ligase Complex	Nuclear Chromatin Nucleus
	Molecular Function	Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Cell Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Negative Regulation Of Transcription By RNA Polymerase II Blood Vessel Development Regulation Of Transcription By RNA Polymerase II Embryo Development Animal Organ Morphogenesis Anterior/posterior Axis Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Labyrinthine Layer Development
Pathways		SCF(Skp2)-mediated degradation of p27/p21 Cyclin D associated events in G1
Drugs		Fluoxetine Meta Vanadate
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732)
Interacting Genes		32 interacting genes: AP2M1 ARID5A CBY2 CCNA1 CCNB2 CDC27 CDC37 CDK2 CDKN1B CDX4 CKS1BP7 CKS2 CUL1 DUSP1 ECPAS HSP90AA1 IKZF1 KRTAP10-9 KRTAP5-9 LDHB MEOX1 MIPOL1 PSMD9 REL ROPN1 SEPTIN3 SKP2 SSBP1 SUMO1P1 TCF4 TRIM27 XIAP	8 interacting genes: BANP CKS1B HOXA5 LMO1 LMO2 PITX1 PRKAA1 PRKAB2
Entrez ID		1163	1046
HPRD ID		00299	02065
Ensembl ID		ENSG00000173207	ENSG00000131264
Uniprot IDs		P61024 Q5T178	O14627
PDB IDs		1BUH 1DKS 1DKT 2ASS 2AST 4YC6
Enriched GO Terms of Interacting Partners?
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