ROPN1 and LNX2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		ROPN1	LNX2
Description		rhophilin associated tail protein 1	ligand of numb-protein X 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Motile Cilium
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Protein Phosphorylation Flagellated Sperm Motility Cilium Organization Sperm Capacitation Protein Localization To Cilium
Pathways		RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Household income ( 31844048) Household income (MTAG) ( 31844048)	Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		26 interacting genes: AKAP3 AKAP7 CEP57L1 CKS1B CNST FAM162A GNL3L GPKOW HNRNPUL1 KIF9 LENG1 LNX1 LNX2 NTAQ1 POLR3C PRKAA1 PSMA1 RHPN1 RTP5 SDCBP SERTAD1 SPA17 TSNAXIP1 TULP3 UBE2W XKR3	89 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581
Entrez ID		54763	222484
HPRD ID		15269	10042
Ensembl ID		ENSG00000065371	ENSG00000139517
Uniprot IDs		A0A140VKB2 Q9HAT0	Q8N448
PDB IDs			2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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