CKS1B and ARID5A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CKS1B	ARID5A
Description		CDC28 protein kinase regulatory subunit 1B	AT-rich interaction domain 5A
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleoplasm SCF Ubiquitin Ligase Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Protein Kinase Binding Histone Binding Ubiquitin Binding Cyclin-dependent Protein Serine/threonine Kinase Activator Activity	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Estrogen Receptor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Cell Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Innate Immune Response Negative Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		SCF(Skp2)-mediated degradation of p27/p21 Cyclin D associated events in G1
Drugs		Fluoxetine Meta Vanadate
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Prostate cancer ( 23535732)	Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Event-related brain oscillations ( 21184583)
Interacting Genes		32 interacting genes: AP2M1 ARID5A CBY2 CCNA1 CCNB2 CDC27 CDC37 CDK2 CDKN1B CDX4 CKS1BP7 CKS2 CUL1 DUSP1 ECPAS HSP90AA1 IKZF1 KRTAP10-9 KRTAP5-9 LDHB MEOX1 MIPOL1 PSMD9 REL ROPN1 SEPTIN3 SKP2 SSBP1 SUMO1P1 TCF4 TRIM27 XIAP	19 interacting genes: AR ATXN1 CKS1B DAB1 DAZAP2 ESR2 GOLGA2 KRT40 KRTAP12-2 KRTAP12-4 MDFI PNMA1 RARA RBPMS RHOXF2 RXRA SH2D2A SOX5 THRA
Entrez ID		1163	10865
HPRD ID		00299	12481
Ensembl ID		ENSG00000173207	ENSG00000196843
Uniprot IDs		P61024 Q5T178	Q03989
PDB IDs		1BUH 1DKS 1DKT 2ASS 2AST 4YC6
Enriched GO Terms of Interacting Partners?
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