SGTB and TXNDC12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		SGTB	TXNDC12
Description		small glutamine rich tetratricopeptide repeat containing beta	thioredoxin domain containing 12
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane TRC Complex	Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Molecular Adaptor Activity	Protein Binding Peptide Disulfide Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding	Cell Redox Homeostasis Oxidation-reduction Process Negative Regulation Of Cell Death Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs			Glutathione
Diseases
GWAS
Interacting Genes		11 interacting genes: COL1A2 CWC27 EFEMP2 IL6ST LAMP3 PPIB RAI2 SERPINE1 SERPINI2 TMPO TXNDC12	5 interacting genes: KLHL2 SGTA SGTB UBQLN1 ZDHHC17
Entrez ID		54557	51060
HPRD ID		18049	11633
Ensembl ID		ENSG00000197860	ENSG00000117862
Uniprot IDs		Q96EQ0	O95881
PDB IDs			1SEN 2K8V
Enriched GO Terms of Interacting Partners?
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