TXNDC12 and SGTB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TXNDC12	SGTB
Description		thioredoxin domain containing 12	small glutamine rich tetratricopeptide repeat containing beta
Image			No pdb structure
GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Cytosol Membrane TRC Complex
	Molecular Function	Protein Binding Peptide Disulfide Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity	Protein Binding Molecular Adaptor Activity
	Biological Process	Cell Redox Homeostasis Oxidation-reduction Process Negative Regulation Of Cell Death Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding
Pathways
Drugs		Glutathione
Diseases
GWAS
Interacting Genes		5 interacting genes: KLHL2 SGTA SGTB UBQLN1 ZDHHC17	11 interacting genes: COL1A2 CWC27 EFEMP2 IL6ST LAMP3 PPIB RAI2 SERPINE1 SERPINI2 TMPO TXNDC12
Entrez ID		51060	54557
HPRD ID		11633	18049
Ensembl ID		ENSG00000117862	ENSG00000197860
Uniprot IDs		O95881	Q96EQ0
PDB IDs		1SEN 2K8V
Enriched GO Terms of Interacting Partners?
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