SGTB and CWC27

		SGTB	CWC27
Description		small glutamine rich tetratricopeptide repeat containing beta	CWC27 spliceosome associated cyclophilin
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane TRC Complex	Nucleoplasm U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Molecular Adaptor Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Cyclosporin A Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Ubiquitin-dependent ERAD Pathway Positive Regulation Of Chaperone-mediated Protein Folding	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bladder cancer ( 27206850) Central corneal thickness ( 31798171 29760442) Diverticular disease ( 30177863) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Obesity-related traits ( 23251661) Systolic blood pressure ( 30224653) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)
Interacting Genes		11 interacting genes: COL1A2 CWC27 EFEMP2 IL6ST LAMP3 PPIB RAI2 SERPINE1 SERPINI2 TMPO TXNDC12	10 interacting genes: CLK1 ERBIN FRA10AC1 GTF2H2 HMGA1 NLN PPWD1 RNF180 SGTB TRAPPC13
Entrez ID		54557	10283
HPRD ID		18049	11541
Ensembl ID		ENSG00000197860	ENSG00000153015
Uniprot IDs		Q96EQ0	D6REK3 Q6UX04
PDB IDs			2HQ6 4R3E 5Z56 5Z58 6FF4 6FF7
Enriched GO Terms of Interacting Partners?
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