TXNDC12 and KLHL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		TXNDC12	KLHL2
Description		thioredoxin domain containing 12	kelch like family member 2
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GO Annotations	Cellular Component	Cell Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Peptide Disulfide Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity	Actin Binding Protein Binding Identical Protein Binding
	Biological Process	Cell Redox Homeostasis Oxidation-reduction Process Negative Regulation Of Cell Death Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Protein Ubiquitination Post-translational Protein Modification
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Glutathione
Diseases
GWAS			Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		5 interacting genes: KLHL2 SGTA SGTB UBQLN1 ZDHHC17	15 interacting genes: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114
Entrez ID		51060	11275
HPRD ID		11633	09311
Ensembl ID		ENSG00000117862	ENSG00000109466
Uniprot IDs		O95881	B4DFZ5 E9PEX9 O95198
PDB IDs		1SEN 2K8V	2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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