CWC27 and RNF180

		CWC27	RNF180
Description		CWC27 spliceosome associated cyclophilin	ring finger protein 180
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nuclear Envelope Integral Component Of Membrane Intrinsic Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Cyclosporin A Binding	Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding	Protein Polyubiquitination Adult Behavior Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Norepinephrine Metabolic Process Serotonin Metabolic Process Regulation Of Catalytic Activity
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Bladder cancer ( 27206850) Central corneal thickness ( 31798171 29760442) Diverticular disease ( 30177863) Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Obesity-related traits ( 23251661) Systolic blood pressure ( 30224653) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Body mass index ( 26426971) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: CLK1 ERBIN FRA10AC1 GTF2H2 HMGA1 NLN PPWD1 RNF180 SGTB TRAPPC13	1 interacting genes: CWC27
Entrez ID		10283	285671
HPRD ID		11541	15263
Ensembl ID		ENSG00000153015	ENSG00000164197
Uniprot IDs		D6REK3 Q6UX04	Q86T96
PDB IDs		2HQ6 4R3E 5Z56 5Z58 6FF4 6FF7
Enriched GO Terms of Interacting Partners?
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