NECAB2 and ISCU

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		NECAB2	ISCU
Description		N-terminal EF-hand calcium binding protein 2	iron-sulfur cluster assembly enzyme
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Cell Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	Iron Ion Binding Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Cellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Small Molecule Metabolic Process Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Aconitate Hydratase Activity Negative Regulation Of Ferrous Iron Import Across Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)	Acne (severe) ( 24927181) Intraocular pressure ( 29617998)
Interacting Genes		63 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C1orf109 CAPN3 CARD9 CCDC121 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NIP7 NOC4L NTAQ1 PCM1 POLR2C PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USHBP1 USP7 VTA1	13 interacting genes: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 HSCB IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62
Entrez ID		54550	23479
HPRD ID		13263	14828
Ensembl ID		ENSG00000103154	ENSG00000136003
Uniprot IDs		Q7Z6G3	A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1
PDB IDs			5KZ5 5WKP 5WLW 6NZU 6UXE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?