NECAB2 and INPP1

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		NECAB2	INPP1
Description		N-terminal EF-hand calcium binding protein 2	inositol polyphosphate-1-phosphatase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	Inositol-1,4-bisphosphate 1-phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation
Pathways			Synthesis of IP2, IP, and Ins in the cytosol
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)	Daytime sleep phenotypes ( 27126917) Lung cancer (SNP x SNP interaction) ( 24325914)
Interacting Genes		63 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C1orf109 CAPN3 CARD9 CCDC121 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NIP7 NOC4L NTAQ1 PCM1 POLR2C PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USHBP1 USP7 VTA1	11 interacting genes: BRCA1 C9orf16 DYNLL1 LDOC1 LIG1 MEOX2 NDC80 NECAB2 NR1D1 SYCE3 USHBP1
Entrez ID		54550	3628
HPRD ID		13263	00923
Ensembl ID		ENSG00000103154	ENSG00000151689
Uniprot IDs		Q7Z6G3	P49441 Q6IBG4
PDB IDs
Enriched GO Terms of Interacting Partners?
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