ISCU and HSCB

Number of citations of the paper that reports this interaction (PubMedID 24573684)
9

Data Source:
BioGRID (pull down, affinity chromatography technology)

		ISCU	HSCB
Description		iron-sulfur cluster assembly enzyme	HscB mitochondrial iron-sulfur cluster cochaperone
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GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Molecular Adaptor Activity	ATPase Activator Activity Molecular_function Protein Binding Identical Protein Binding Metal Ion Binding Chaperone Binding
	Biological Process	Cellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Small Molecule Metabolic Process Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Aconitate Hydratase Activity Negative Regulation Of Ferrous Iron Import Across Plasma Membrane	Iron-sulfur Cluster Assembly Positive Regulation Of ATPase Activity [2Fe-2S] Cluster Assembly Protein Complex Oligomerization Protein Maturation By Iron-sulfur Cluster Transfer
Pathways			Mitochondrial protein import Mitochondrial protein import Mitochondrial iron-sulfur cluster biogenesis
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Intraocular pressure ( 29617998)	Breast size ( 27182965) Diastolic blood pressure ( 27841878) Esophageal cancer and gastric cancer ( 20729852) Pancreatic cancer ( 25086665) Red cell distribution width ( 27863252) Systolic blood pressure ( 27841878)
Interacting Genes		13 interacting genes: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 HSCB IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62	6 interacting genes: AGTRAP BBS1 BBS2 BBS4 FBN1 ISCU
Entrez ID		23479	150274
HPRD ID		14828	16289
Ensembl ID		ENSG00000136003	ENSG00000100209
Uniprot IDs		A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1	A0A384NYJ4 B0QYH2 Q8IWL3
PDB IDs		5KZ5 5WKP 5WLW 6NZU 6UXE	3BVO
Enriched GO Terms of Interacting Partners?
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