ISCU and MID2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ISCU	MID2
Description		iron-sulfur cluster assembly enzyme	midline 2
Image
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Cytoplasm Microtubule Extracellular Exosome
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Molecular Adaptor Activity	Microtubule Binding Zinc Ion Binding Transferase Activity Enzyme Binding Protein Homodimerization Activity Phosphoprotein Binding
	Biological Process	Cellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Small Molecule Metabolic Process Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Aconitate Hydratase Activity Negative Regulation Of Ferrous Iron Import Across Plasma Membrane	Positive Regulation Of Autophagy Protein Ubiquitination Negative Regulation Of Viral Transcription Protein Localization To Microtubule Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Viral Release From Host Cell
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Intraocular pressure ( 29617998)
Interacting Genes		13 interacting genes: AGTRAP BANP CCDC172 FAM9B GOLGA2 HPRT1 HSCB IKZF1 KRT40 LNX1 MID2 NECAB2 NUP62	118 interacting genes: ADAMTSL4 AEN AQP1 ATRIP AXIN1 BCL6B BRCA1 BRMS1L BYSL CALCOCO2 CBX8 CCDC120 CCDC42 CCHCR1 CEP57L1 CHD2 COX5B CTSZ DCX DGCR6 DGCR6L DMRT3 DYDC1 ELOA FAM107A FAM161A FAM214A FAM90A1 FARS2 FBF1 FBXL18 FRMD6 GFI1B GMCL1 GOLGA2 GORASP2 HNRNPLL HOXB9 IGBP1 IQCN ISCU JOSD1 KIF1A KIFC3 LENG1 LGALS14 LGALS8 MAGOHB METTL17 MFAP1 MID1 MID1IP1 MOS MVP NR1D2 NXF1 OTUB2 PPP1R18 PRPF3 PRPF31 PSMA1 PTCD2 RCOR3 RNF6 RPH3AL RPP25L RUNX1T1 RXRB SCNM1 SDCBP SHFL SLC25A48 SLC25A6 SNAI1 SNAP47 SPAG5 SPATA24 SPG21 SPRY2 STX11 TCAF1 TCEA2 THAP7 TMEM14B TOP3B TRIM27 TRIM29 TRIM32 TRIM42 TRIM54 TRPV6 TSGA10 UBE2D1 UBE2D4 UBE2E2 UBE2E3 UBE2U UBTD1 UNC45A UTP23 UTP25 WT1-AS ZBTB24 ZC2HC1C ZFYVE21 ZGPAT ZNF165 ZNF24 ZNF250 ZNF417 ZNF440 ZNF564 ZNF587 ZNF688 ZNF774 ZNF785 ZNF792 ZSCAN12
Entrez ID		23479	11043
HPRD ID		14828	02191
Ensembl ID		ENSG00000136003	ENSG00000080561
Uniprot IDs		A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1	Q6GX22 Q9UJV3
PDB IDs		5KZ5 5WKP 5WLW 6NZU 6UXE	2DJA 2DMK
Enriched GO Terms of Interacting Partners?
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