NECAB2 and RCOR3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		NECAB2	RCOR3
Description		N-terminal EF-hand calcium binding protein 2	REST corepressor 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Nucleus Transcriptional Repressor Complex
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)
Interacting Genes		63 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C1orf109 CAPN3 CARD9 CCDC121 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NIP7 NOC4L NTAQ1 PCM1 POLR2C PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USHBP1 USP7 VTA1	32 interacting genes: APP CCDC102B CDR2 CEP55 CEP70 GOLGA2 GSE1 IKZF3 KDM1A KRT15 KRT31 KRT40 LCA5 LUZP4 LZTS2 MAGEA6 MARK3 MID2 MIPOL1 NECAB2 NINL PHF21B PRDM14 SUMO2 TFIP11 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TXLNA YWHAQ
Entrez ID		54550	55758
HPRD ID		13263	08338
Ensembl ID		ENSG00000103154	ENSG00000117625
Uniprot IDs		Q7Z6G3	Q9P2K3
PDB IDs			4CZZ
Enriched GO Terms of Interacting Partners?
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