FBXW5 and UBE2R2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		FBXW5	UBE2R2
Description		F-box and WD repeat domain containing 5	ubiquitin conjugating enzyme E2 R2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Conjugating Enzyme Activity
	Biological Process	Protein Polyubiquitination Regulation Of Mitotic Nuclear Division Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Protein Monoubiquitination Protein Ubiquitination Protein K48-linked Ubiquitination
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Synthesis of active ubiquitin: roles of E1 and E2 enzymes Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Heel bone mineral density ( 30598549)	Bipolar disorder ( 20351715) Body mass index ( 25673413) Estimated glomerular filtration rate ( 31015462) Health literacy ( 31250787)
Interacting Genes		19 interacting genes: ADAMTSL4 FAM168A KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NLA S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2	25 interacting genes: APPBP2 ARHGDIA ARIH2 BTRC CBLC CSNK2A1 CSNK2A2 CTNNB1 CUL3 DTX3L DZIP3 FBXW5 INF2 ITCH MAEA MDM2 MEOX1 MUL1 PNPLA2 PRKN RBX1 RNF113B RNF31 UBA1 UBC
Entrez ID		54461	54926
HPRD ID		10955	15602
Ensembl ID		ENSG00000159069	ENSG00000107341
Uniprot IDs		A0A024R8H7 Q969U6	Q712K3
PDB IDs			6NYO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?