FBXW5 and SEC23B

Number of citations of the paper that reports this interaction (PubMedID 30596474)
6

Data Source:
BioGRID (affinity chromatography technology, unspecified method, affinity chromatography technology)

		FBXW5	SEC23B
Description		F-box and WD repeat domain containing 5	SEC23 homolog B, COPII coat complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding Protein Kinase Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Polyubiquitination Regulation Of Mitotic Nuclear Division Regulation Of Centrosome Duplication Protein Ubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Intracellular Protein Transport Positive Regulation Of GTPase Activity Cargo Loading Into COPII-coated Vesicle
Pathways		Association of TriC/CCT with target proteins during biosynthesis Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Blood protein levels ( 29875488) Heel bone mineral density ( 30598549)
Interacting Genes		19 interacting genes: ADAMTSL4 FAM168A KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NLA S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2	21 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 SEC24C SEC24D SKP1 SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1
Entrez ID		54461	10483
HPRD ID		10955	11543
Ensembl ID		ENSG00000159069	ENSG00000101310
Uniprot IDs		A0A024R8H7 Q969U6	A0A2R8YFH5 Q15437
PDB IDs
Enriched GO Terms of Interacting Partners?
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