PITX1 and TRAPPC2

Number of citations of the paper that reports this interaction (PubMedID 20498720)
11

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		PITX1	TRAPPC2
Description		paired like homeodomain 1	trafficking protein particle complex 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Cytoplasm	Golgi Membrane Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Protein Binding Transcription Factor Binding Ion Channel Binding
	Biological Process	Skeletal System Development Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Myoblast Fate Commitment Cartilage Development	Skeletal System Development Regulation Of Transcription, DNA-templated ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating
Pathways			COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Congenital clubfoot; Congenital talipes equinovarus	Spondyloepiphyseal dysplasia tarda
GWAS		Atrial fibrillation ( 29237688) Bulimia nervosa ( 23568457) Colorectal cancer ( 30529582 24836286 23263487) Colorectal cancer or advanced adenoma ( 30510241) Height ( 20881960 25429064 23563607 31562340 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 28604732 23666240)
Interacting Genes		27 interacting genes: ALG13 C1orf94 CDX4 DVL3 EGR1 FOXO1 GOLGA2 HGS IPO13 LZTS2 MAGED1 MGAT5B NEUROD1 NR5A1 PLSCR1 POU1F1 PRR20A RBPMS RFX6 RHOXF2 RNF31 SMARCA2 SPAG8 TRAPPC2 TRIM23 UPF2 ZBTB32	14 interacting genes: CLIC1 CLIC2 DAPK1 ENO1 MFHAS1 NR5A1 PITX1 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		5307	6399
HPRD ID		03688	02189
Ensembl ID		ENSG00000069011	ENSG00000196459
Uniprot IDs		P78337 X5D9A5	P0DI81 P0DI82 Q6IBE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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