PITX1 and MGAT5B

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		PITX1	MGAT5B
Description		paired like homeodomain 1	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex Cytoplasm	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Protein Binding Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding
	Biological Process	Skeletal System Development Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Myoblast Fate Commitment Cartilage Development	Protein N-linked Glycosylation Protein O-linked Glycosylation Via Serine
Pathways
Drugs
Diseases		Congenital clubfoot; Congenital talipes equinovarus
GWAS		Atrial fibrillation ( 29237688) Bulimia nervosa ( 23568457) Colorectal cancer ( 30529582 24836286 23263487) Colorectal cancer or advanced adenoma ( 30510241) Height ( 20881960 25429064 23563607 31562340 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 28604732 23666240)	Cannabis use (initiation) ( 22823124) Colorectal or endometrial cancer ( 26621817) Early cardiac repolarization ( 22683750) Pulmonary emphysema ( 24383474) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)
Interacting Genes		27 interacting genes: ALG13 C1orf94 CDX4 DVL3 EGR1 FOXO1 GOLGA2 HGS IPO13 LZTS2 MAGED1 MGAT5B NEUROD1 NR5A1 PLSCR1 POU1F1 PRR20A RBPMS RFX6 RHOXF2 RNF31 SMARCA2 SPAG8 TRAPPC2 TRIM23 UPF2 ZBTB32	22 interacting genes: CAMK2B CREB5 DMRT3 EIF4ENIF1 FAM83A FNDC11 HOXA1 KLHL38 KRTAP12-2 KRTAP19-5 KRTAP26-1 MDFI OTX1 PITX1 PLSCR1 PTGER3 PTPRZ1 RBPMS STK16 TRIP13 TXNDC5 VAC14
Entrez ID		5307	146664
HPRD ID		03688	14392
Ensembl ID		ENSG00000069011	ENSG00000167889
Uniprot IDs		P78337 X5D9A5	Q3V5L5
PDB IDs
Enriched GO Terms of Interacting Partners?
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