TRAPPC2 and ENO1

Number of citations of the paper that reports this interaction (PubMedID 11134351)
10

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)

		TRAPPC2	ENO1
Description		trafficking protein particle complex 2	enolase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cell Surface Membrane M Band Extracellular Exosome Cell Cortex Region
	Molecular Function	Protein Binding Transcription Factor Binding Ion Channel Binding	Magnesium Ion Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Binding Phosphopyruvate Hydratase Activity Protein Binding Protein Homodimerization Activity Cadherin Binding GTPase Binding
	Biological Process	Skeletal System Development Regulation Of Transcription, DNA-templated ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Negative Regulation Of Transcription By RNA Polymerase II Gluconeogenesis Response To Virus Positive Regulation Of Plasminogen Activation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Muscle Contraction Canonical Glycolysis Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Biosynthetic Process
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Glycolysis Gluconeogenesis Manipulation of host energy metabolism
Drugs			Zinc Copper Artenimol
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS			Asthma ( 30929738) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood protein levels ( 30072576) Feeling tense ( 29500382) Plateletcrit ( 27863252) Tonsillectomy ( 27182965 28928442) White blood cell count (basophil) ( 27863252)
Interacting Genes		14 interacting genes: CLIC1 CLIC2 DAPK1 ENO1 MFHAS1 NR5A1 PITX1 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9	26 interacting genes: AGTPBP1 AMBP BHLHE40 BRCA1 CHEK2 CLK1 FANCA FYN GRB2 HDAC1 HEMGN HSPB2 LIG4 MCPH1 MYOC PCNA PLG SERPING1 SRC SUMO2 SUMO4 TERT TRAPPC2 UPF2 YWHAQ YWHAZ
Entrez ID		6399	2023
HPRD ID		02189	01400
Ensembl ID		ENSG00000196459	ENSG00000074800
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	A0A024R4F1 P06733
PDB IDs			2PSN 3B97 5JLZ 5LAX 5NI9 5NIG 5OCK
Enriched GO Terms of Interacting Partners?
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