MGAT5B and PTGER3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MGAT5B	PTGER3
Description		alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	prostaglandin E receptor 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Cell Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Manganese Ion Binding	Prostaglandin E Receptor Activity
	Biological Process	Protein N-linked Glycosylation Protein O-linked Glycosylation Via Serine	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion
Pathways			Prostanoid ligand receptors G alpha (i) signalling events
Drugs			Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Colorectal or endometrial cancer ( 26621817) Early cardiac repolarization ( 22683750) Pulmonary emphysema ( 24383474) Virologic severity in Herpes simplex virus type 2 infection ( 29535370)	Dental caries (decayed, missing and filled teeth) ( 31533690) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)
Interacting Genes		22 interacting genes: CAMK2B CREB5 DMRT3 EIF4ENIF1 FAM83A FNDC11 HOXA1 KLHL38 KRTAP12-2 KRTAP19-5 KRTAP26-1 MDFI OTX1 PITX1 PLSCR1 PTGER3 PTPRZ1 RBPMS STK16 TRIP13 TXNDC5 VAC14	23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		146664	5733
HPRD ID		14392	08906
Ensembl ID		ENSG00000167889	ENSG00000050628
Uniprot IDs		Q3V5L5	O00325 P43115
PDB IDs			6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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