TNFRSF12A and TRAF5

Number of citations of the paper that reports this interaction (PubMedID 12529173)
65

Data Source:
HPRD (two hybrid, in vitro)

		TNFRSF12A	TRAF5
Description		TNF receptor superfamily member 12A	TNF receptor associated factor 5
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Plasma Membrane Cell Surface Integral Component Of Membrane	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding
	Biological Process	Angiogenesis Substrate-dependent Cell Migration, Cell Attachment To Substrate Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Angiogenesis Positive Regulation Of Axon Extension Regulation Of Wound Healing Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination
Pathways		TNFR2 non-canonical NF-kB pathway TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Drugs
Diseases
GWAS			Household income (MTAG) ( 31844048)
Interacting Genes		7 interacting genes: RAC1 SLC30A2 TNFSF12 TRAF1 TRAF2 TRAF3 TRAF5	45 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GOLGA2 GORASP2 HSD17B10 LTBR MAP3K14 MAP3K5 MDM2 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TBK1 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 ZFAND6
Entrez ID		51330	7188
HPRD ID		05801	03834
Ensembl ID		ENSG00000006327	ENSG00000082512
Uniprot IDs		Q9NP84	O00463
PDB IDs		2EQP 2KMZ 2RPJ
Enriched GO Terms of Interacting Partners?
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