KLHL2 and CCDC43

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		KLHL2	CCDC43
Description		kelch like family member 2	coiled-coil domain containing 43
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Cytosol Actin Cytoskeleton Lamellipodium Cul3-RING Ubiquitin Ligase Complex	Cytosol
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Protein Ubiquitination Post-translational Protein Modification
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 24684796) General cognitive ability ( 29844566) Neuroticism ( 27067015)
Interacting Genes		15 interacting genes: ACTC1 BCAM CCDC43 CLK2 CUL3 KLHL12 SDCBP TMA16 TNPO2 TXNDC12 UBE2C UBE2D1 WNK1 WNK4 ZNF114	4 interacting genes: KLHL2 LRRK2 MFHAS1 TINF2
Entrez ID		11275	124808
HPRD ID		09311	08107
Ensembl ID		ENSG00000109466	ENSG00000180329
Uniprot IDs		B4DFZ5 E9PEX9 O95198	Q96MW1
PDB IDs		2XN4 4CHB
Enriched GO Terms of Interacting Partners?
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