MST1R and GJB1

Number of citations of the paper that reports this interaction (PubMedID 30401746)
0

Data Source:
BioGRID (enzymatic study)

		MST1R	GJB1
Description		macrophage stimulating 1 receptor	gap junction protein beta 1
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GO Annotations	Cellular Component	Stress Fiber Vacuole Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Cell Surface Receptor Complex	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane Lateral Plasma Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Macrophage Colony-stimulating Factor Receptor Activity Protein Binding ATP Binding Enzyme Binding	Gap Junction Channel Activity
	Biological Process	Defense Response Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Single Fertilization Positive Regulation Of Cell Proliferation Response To Virus Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of MAP Kinase Activity Innate Immune Response Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling	Cell-cell Signaling Nervous System Development Purine Ribonucleotide Transport Gap Junction Assembly Transmembrane Transport Epididymis Development
Pathways		Signaling by MST1	Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Age at first birth ( 27798627) Body mass index ( 26426971 29273807) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 23128233) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 25082827)
Interacting Genes		25 interacting genes: AKT1 EPOR ERBB2 GAB1 GJB1 GPX1 GRB2 HYAL2 JAK2 MST1 PIK3R1 PLCG1 PPP1CA PTPRR RELA SFN SHC1 SRC STUB1 YES1 YWHAB YWHAE YWHAH YWHAQ YWHAZ	13 interacting genes: APP CALM1 CNST EGFR EPHA1 GJB2 GLP1R MST1R PRKACA PRKCA PTPN2 SRC VKORC1
Entrez ID		4486	2705
HPRD ID		02545	02367
Ensembl ID		ENSG00000164078	ENSG00000169562
Uniprot IDs		B4E058 G9JXB8 Q04912	P08034
PDB IDs		3PLS 4FWW 4QT8	1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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