GJB1 and MST1R

Number of citations of the paper that reports this interaction (PubMedID 30401746)
0

Data Source:
BioGRID (enzymatic study)

		GJB1	MST1R
Description		gap junction protein beta 1	macrophage stimulating 1 receptor
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane Lateral Plasma Membrane	Stress Fiber Vacuole Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Cell Surface Receptor Complex
	Molecular Function	Gap Junction Channel Activity	Transmembrane Receptor Protein Tyrosine Kinase Activity Macrophage Colony-stimulating Factor Receptor Activity Protein Binding ATP Binding Enzyme Binding
	Biological Process	Cell-cell Signaling Nervous System Development Purine Ribonucleotide Transport Gap Junction Assembly Transmembrane Transport Epididymis Development	Defense Response Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Single Fertilization Positive Regulation Of Cell Proliferation Response To Virus Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of MAP Kinase Activity Innate Immune Response Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling
Pathways		Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly	Signaling by MST1
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS			Age at first birth ( 27798627) Body mass index ( 26426971 29273807) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 23128233) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 25082827)
Interacting Genes		13 interacting genes: APP CALM1 CNST EGFR EPHA1 GJB2 GLP1R MST1R PRKACA PRKCA PTPN2 SRC VKORC1	25 interacting genes: AKT1 EPOR ERBB2 GAB1 GJB1 GPX1 GRB2 HYAL2 JAK2 MST1 PIK3R1 PLCG1 PPP1CA PTPRR RELA SFN SHC1 SRC STUB1 YES1 YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		2705	4486
HPRD ID		02367	02545
Ensembl ID		ENSG00000169562	ENSG00000164078
Uniprot IDs		P08034	B4E058 G9JXB8 Q04912
PDB IDs		1TXH 5KK9	3PLS 4FWW 4QT8
Enriched GO Terms of Interacting Partners?
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