MST1R and HYAL2

Number of citations of the paper that reports this interaction (PubMedID 12676986)
36

Data Source:
HPRD (in vivo)

		MST1R	HYAL2
Description		macrophage stimulating 1 receptor	hyaluronidase 2
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Vacuole Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Cell Surface Receptor Complex	Golgi Membrane Cytoplasm Lysosome Endoplasmic Reticulum Cytosol Plasma Membrane Microvillus Cell Surface Apical Plasma Membrane Endocytic Vesicle Anchored Component Of External Side Of Plasma Membrane Cytoplasmic Vesicle Membrane Raft Anchored Component Of Plasma Membrane Perinuclear Region Of Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Activity Macrophage Colony-stimulating Factor Receptor Activity Protein Binding ATP Binding Enzyme Binding	Virus Receptor Activity Transcription Coactivator Activity Hyalurononglucosaminidase Activity Protein Binding Hyaluronic Acid Binding Enzyme Binding Receptor Signaling Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Hyaluronoglucuronidase Activity Transforming Growth Factor Beta Binding
	Biological Process	Defense Response Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Single Fertilization Positive Regulation Of Cell Proliferation Response To Virus Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of MAP Kinase Activity Innate Immune Response Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling	Response To Reactive Oxygen Species Kidney Development Hematopoietic Progenitor Cell Differentiation Carbohydrate Metabolic Process Glycosaminoglycan Catabolic Process Response To Virus Multicellular Organism Aging Negative Regulation Of Fibroblast Migration Fusion Of Virus Membrane With Host Plasma Membrane Transformation Of Host Cell By Virus Hyaluronan Catabolic Process Negative Regulation Of Cell Growth Positive Regulation Of Urine Volume Monocyte Activation Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of MAP Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Response To Antibiotic Viral Entry Into Host Cell Skeletal System Morphogenesis Positive Regulation Of Inflammatory Response Cartilage Development Defense Response To Virus Negative Regulation Of Protein Kinase B Signaling Multicellular Organismal Iron Ion Homeostasis Negative Regulation Of Protein Tyrosine Kinase Activity Renal Water Absorption Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To UV-B Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Interleukin-8 Secretion Positive Regulation Of Interleukin-6 Secretion Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Signaling by MST1	Hyaluronan uptake and degradation
Drugs
Diseases
GWAS		Age at first birth ( 27798627) Body mass index ( 26426971 29273807) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 23128233) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 25082827)	Body mass index ( 26426971) Sleep duration (short sleep) ( 30846698)
Interacting Genes		25 interacting genes: AKT1 EPOR ERBB2 GAB1 GJB1 GPX1 GRB2 HYAL2 JAK2 MST1 PIK3R1 PLCG1 PPP1CA PTPRR RELA SFN SHC1 SRC STUB1 YES1 YWHAB YWHAE YWHAH YWHAQ YWHAZ	8 interacting genes: FHL3 KRTAP10-3 KRTAP3-2 MST1R SMAD2 SMAD3 SMAD4 WWOX
Entrez ID		4486	8692
HPRD ID		02545	04649
Ensembl ID		ENSG00000164078	ENSG00000068001
Uniprot IDs		B4E058 G9JXB8 Q04912	Q12891
PDB IDs		3PLS 4FWW 4QT8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?