MSH4 and DMC1

Number of citations of the paper that reports this interaction (PubMedID 15489243)
16

Data Source:
BioGRID (two hybrid, pull down)

		MSH4	DMC1
Description		mutS homolog 4	DNA meiotic recombinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Synaptonemal Complex Nucleus Recombination Nodule	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome
	Molecular Function	DNA Binding Protein Binding DNA-dependent ATPase Activity Mismatched DNA Binding	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Ovarian Follicle Development Mismatch Repair Synapsis Reciprocal Meiotic Recombination Spermatogenesis Female Gamete Generation	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Synapsis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Response To Ionizing Radiation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle
Pathways		Meiotic recombination	Meiotic recombination
Drugs			Imidazole
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813) Daytime sleep phenotypes ( 27126917) Serum metabolite levels ( 23093944)	Gamma glutamyl transferase levels ( 29403010) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)
Interacting Genes		9 interacting genes: ACADM DMC1 EIF3F MLH1 MLH3 MSH5 RAD51 RPA1 VBP1	14 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 MSH4 NIF3L1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP TRIM23
Entrez ID		4438	11144
HPRD ID		03658	04099
Ensembl ID		ENSG00000057468	ENSG00000100206
Uniprot IDs		O15457	Q14565
PDB IDs			1V5W 2ZJB 4HYY 6R3P
Enriched GO Terms of Interacting Partners?
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