DMC1 and NIF3L1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		DMC1	NIF3L1
Description		DNA meiotic recombinase 1	NGG1 interacting factor 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome	Nucleus Cytoplasm Mitochondrion
	Molecular Function	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding	Protein Binding Transcription Factor Binding Identical Protein Binding
	Biological Process	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Synapsis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Response To Ionizing Radiation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		Meiotic recombination
Drugs		Imidazole
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)	Triptolide cytotoxicity ( 26121980)
Interacting Genes		14 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 MSH4 NIF3L1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP TRIM23	67 interacting genes: AP5B1 APIP ARPIN BEND7 CCDC102B CCDC85B CDKN2B CDKN2C COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DUSP23 DYNLT3 EIF5A2 ENOX1 EPHB6 FXR2 GNMT GRB2 KCTD17 KRT15 KXD1 LAMTOR3 LMO2 MAGEA11 MAPRE2 MLXIPL NATD1 NME1 NOL3 NUDT14 NUDT21 ORC5 PAICS PCBD1 PNMA1 PRTFDC1 RABAC1 RAD54B RPIA S100A1 SAT1 SNF8 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SYT17 THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 VIM YES1 YWHAQ ZBED1
Entrez ID		11144	60491
HPRD ID		04099	10424
Ensembl ID		ENSG00000100206	ENSG00000196290
Uniprot IDs		Q14565	A0A024R3V5 A0A024R3V7 Q9GZT8
PDB IDs		1V5W 2ZJB 4HYY 6R3P
Enriched GO Terms of Interacting Partners?
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