DMC1 and KCTD17

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		DMC1	KCTD17
Description		DNA meiotic recombinase 1	potassium channel tetramerization domain containing 17
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome	Cytoplasm Endoplasmic Reticulum Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Recombinase Activity DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity Identical Protein Binding	Protein Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	DNA Recombinase Assembly Ovarian Follicle Development Oocyte Maturation Mitotic Recombination Synapsis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Response To Ionizing Radiation Strand Invasion Meiotic Cell Cycle Chromosome Organization Involved In Meiotic Cell Cycle	Cell Projection Organization Endoplasmic Reticulum Calcium Ion Homeostasis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cilium Assembly Protein Homooligomerization
Pathways		Meiotic recombination
Drugs		Imidazole
Diseases
GWAS		Gamma glutamyl transferase levels ( 29403010) Menopause (age at onset) ( 26414677) Sleep duration ( 30846698)	Iron status biomarkers (ferritin levels) ( 28334935) Mean corpuscular hemoglobin concentration ( 28453575) Red blood cell traits ( 23222517)
Interacting Genes		14 interacting genes: BRCA2 C1orf112 FIGNL1 GORASP2 KCTD17 MSH4 NIF3L1 PSMA3 RAD51 RAD51AP1 RAD54B RPA1 SDCBP TRIM23	19 interacting genes: AQP1 CRK CUL3 DMC1 LNX1 LRRC18 NIF3L1 NUDT18 PLCG2 PSMA1 RBX1 RIN3 RWDD4 STK16 SUV39H2 TCHP TINF2 TUBGCP4 UBE2D1
Entrez ID		11144	79734
HPRD ID		04099	07764
Ensembl ID		ENSG00000100206	ENSG00000100379
Uniprot IDs		Q14565	A0A087WX35 Q8N5Z5
PDB IDs		1V5W 2ZJB 4HYY 6R3P	5A6R
Enriched GO Terms of Interacting Partners?
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