MRE11 and PRKDC

  • Number of citations of the paper that reports this interaction (PubMedID 10608806)
  • 247
  • Data Source:
  • BioGRID (unspecified method)

MRE11

PRKDC

Description MRE11 homolog, double strand break repair nuclease protein kinase, DNA-activated, catalytic subunit
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes 19 interacting genes: ATM ATR CCNE1 CDK2 DCLRE1C DYNLL1 EP300 FANCD2 H2AX LIG1 MAPK8IP2 NBN NEK1 PRKDC RAD50 RECQL5 SPOP SUMO2 XRCC6 89 interacting genes: ABL1 AICDA AKT1 AKT2 AP1B1 ATM ATRIP BRCA1 C1D CASP3 CCNB1 CHEK1 CHEK2 CHUK CIB1 CLK1 CTDP1 DCAF1 DCLRE1C E4F1 EIF2S2 EIF4EBP1 EP300 ERG FH GSK3A GSK3B GZMB H1-1 H1-2 H2AX HDAC3 HMGB1 HMGB2 HNRNPA1 HNRNPC HOXC4 HSF1 HSP90AA1 IKBKB ILF2 JUN KAT2A LIG4 LYN MAPK8 MBP MKNK1 MRE11 MTNR1B NBN NCF1 NCF2 NCF4 NCOA6 NR3C1 PARP1 PCNA PDX1 PGR POU2F1 PPP6C PPP6R1 PPP6R3 PRKCD RAD17 RASSF1 RBBP8 RPA1 RPA2 SGO1 SP1 SRF SUMO2 THRA THRB TOP1 TP53 TREX1 UBE2I USF1 WRN XPA XRCC4 XRCC5 XRCC6 YWHAG YWHAQ ZBTB7A
Entrez ID 4361 5591
HPRD ID 02889 02941
Ensembl ID ENSG00000020922 ENSG00000253729
Uniprot IDs A0A024R395 F8W7U8 P49959 Q05D78 P78527
PDB IDs 3T1I 5LUQ 5W1R 5Y3R
Enriched GO Terms of Interacting Partners?
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