MPP1 and KLHL12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MPP1	KLHL12
Description		membrane palmitoylated protein 1	kelch like family member 12
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GO Annotations	Cellular Component	Intracellular Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	Guanylate Kinase Activity Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways			Degradation of DVL
Drugs
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		22 interacting genes: ABCC4 AMOTL2 ATP5F1C DNPEP ERBIN GADD45A GSK3B GYPC HNRNPD KLHL12 MAP3K20 NR1H2 OPTN RPS6KA1 RPS6KA6 SGSM2 SMN1 SRSF10 STK3 STUB1 TK1 USP21	46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1
Entrez ID		4354	59349
HPRD ID		02370	13925
Ensembl ID		ENSG00000130830	ENSG00000117153
Uniprot IDs		B4E325 Q00013	Q53G59 Q9H7R2
PDB IDs		2EJY 2EV8 3NEY	2VPJ
Enriched GO Terms of Interacting Partners?
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