KLHL12 and CCBE1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KLHL12	CCBE1
Description		kelch like family member 12	collagen and calcium binding EGF domains 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Collagen Trimer Extracellular Space Extracellular Matrix
	Molecular Function	Protein Binding Identical Protein Binding	Protease Binding Calcium Ion Binding Protein Binding Collagen Binding
	Biological Process	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway	Lymphangiogenesis Sprouting Angiogenesis Respiratory System Process Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Protein Processing Lung Development Positive Regulation Of Angiogenesis Venous Blood Vessel Morphogenesis Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Lymphangiogenesis
Pathways		Degradation of DVL
Drugs
Diseases
GWAS			Age-related hearing impairment ( 24939585) Major depressive disorder ( 23857890) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1	6 interacting genes: CEP55 FBXO7 KLHL12 SIAH2 STX11 TOX4
Entrez ID		59349	147372
HPRD ID		13925	08703
Ensembl ID		ENSG00000117153	ENSG00000183287
Uniprot IDs		Q53G59 Q9H7R2	Q6UXH8
PDB IDs		2VPJ
Enriched GO Terms of Interacting Partners?
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