MPP1 and MAP3K20

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MPP1	MAP3K20
Description		membrane palmitoylated protein 1	mitogen-activated protein kinase kinase kinase 20
Image
GO Annotations	Cellular Component	Intracellular Plasma Membrane Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite	Nucleus Cytoplasm Cytosol
	Molecular Function	Guanylate Kinase Activity Protein Binding	Magnesium Ion Binding RNA Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding
	Biological Process	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis	DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Cytoskeleton Organization Cell Cycle Arrest Mitotic Cell Cycle Checkpoint Activation Of JUN Kinase Activity Cell Death Cell Differentiation Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Stress-activated MAPK Cascade Limb Development Cellular Response To Gamma Radiation
Pathways
Drugs			Dasatinib
Diseases
GWAS		Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		22 interacting genes: ABCC4 AMOTL2 ATP5F1C DNPEP ERBIN GADD45A GSK3B GYPC HNRNPD KLHL12 MAP3K20 NR1H2 OPTN RPS6KA1 RPS6KA6 SGSM2 SMN1 SRSF10 STK3 STUB1 TK1 USP21	28 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP2 ZNF33A ZNF567 ZNF593 ZNF746 ZNF775
Entrez ID		4354	51776
HPRD ID		02370	11791
Ensembl ID		ENSG00000130830	ENSG00000091436
Uniprot IDs		B4E325 Q00013	D4Q8H0 Q9NYL2
PDB IDs		2EJY 2EV8 3NEY	5HES 5X5O 6JUT
Enriched GO Terms of Interacting Partners?
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