KLHL12 and VTA1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KLHL12	VTA1
Description		kelch like family member 12	vesicle trafficking 1
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GO Annotations	Cellular Component	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle	Nucleoplasm Multivesicular Body Cytosol Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway	Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Multivesicular Body Sorting Pathway ESCRT III Complex Disassembly
Pathways		Degradation of DVL	Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease ( 30804561) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) FEV1 ( 30804560) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Retinal vascular caliber ( 21060863)
Interacting Genes		46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1	17 interacting genes: APP BEX3 CBS CDK4 CHMP5 DPPA2 KCTD13 KLHL12 LYST MAGEA11 MBIP NBR1 NECAB2 RABAC1 RPIA ZBTB16 ZNRD2
Entrez ID		59349	51534
HPRD ID		13925	09855
Ensembl ID		ENSG00000117153	ENSG00000009844
Uniprot IDs		Q53G59 Q9H7R2	A0A087WY55 Q9NP79
PDB IDs		2VPJ	2LXL 2LXM 4TXP 4TXQ 4TXR 4U7E
Enriched GO Terms of Interacting Partners?
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