CYFIP1 and TCERG1

Number of citations of the paper that reports this interaction (PubMedID 16055720)
81

Data Source:
BioGRID (pull down)

		CYFIP1	TCERG1
Description		cytoplasmic FMR1 interacting protein 1	transcription elongation regulator 1
Image
GO Annotations	Cellular Component	Ruffle Extracellular Region Cytosol MRNA Cap Binding Complex Focal Adhesion Lamellipodium SCAR Complex Filopodium Tip Secretory Granule Lumen Specific Granule Lumen Neuron Projection Neuronal Cell Body Terminal Bouton Dendritic Spine Dendritic Growth Cone Axonal Growth Cone Synapse Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Central Region Of Growth Cone Peripheral Region Of Growth Cone Tertiary Granule Lumen	Nucleus Nucleoplasm
	Molecular Function	RNA 7-methylguanosine Cap Binding Protein Binding Translation Regulator Activity Rac GTPase Binding Actin Filament Binding	RNA Polymerase II Repressing Transcription Factor Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Identical Protein Binding RNA Polymerase Binding Proline-rich Region Binding
	Biological Process	Cell Morphogenesis Regulation Of Translation Axon Guidance Regulation Of Cell Shape Rac Protein Signal Transduction Cell Projection Assembly Lamellipodium Assembly Ruffle Organization Cellular Response To Insulin Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Neutrophil Degranulation Positive Regulation Of Axon Extension Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Extension Cognition Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Response To Electrical Stimulus Dendrite Extension Modification Of Synaptic Structure Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Positive Regulation Of Dendrite Development Positive Regulation Of Ruffle Assembly Negative Regulation Of Synaptic Vesicle Recycling Regulation Of Modification Of Postsynaptic Actin Cytoskeleton Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs Neutrophil degranulation FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Triglyceride levels x loop diuretics use interaction ( 31806883)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		19 interacting genes: ACTA1 APBB1 EFHC2 EFTUD2 FMR1 FXR2 GAS7 GNB1 MEOX1 MYO16 NUP98 NYAP1 NYAP2 PPP1CC PRPF40A RAC1 RFX6 SCTR TCERG1	54 interacting genes: ABI1 AURKA BARD1 BRD4 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 ESR1 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 TPM4 U2AF2 UBE2I WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		23191	10915
HPRD ID		05890	10393
Ensembl ID		ENSG00000273749	ENSG00000113649
Uniprot IDs		Q7L576	O14776
PDB IDs		3P8C 4N78	2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2MW9 2MWA 2MWB 2MWD 2MWE 2MWF 2N4R 2N4S 2N4T 2N4U 2N4V 2N4W 2NNT 3HFH 3Q1I 4FQG
Enriched GO Terms of Interacting Partners?
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