MAP1LC3C and ULK1

Number of citations of the paper that reports this interaction (PubMedID 28253953)
4

Data Source:
BioGRID (pull down)

		MAP1LC3C	ULK1
Description		microtubule associated protein 1 light chain 3 gamma	unc-51 like autophagy activating kinase 1
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GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Microtubule Endomembrane System Organelle Membrane Cytoplasmic Vesicle Cytoplasmic Ribonucleoprotein Granule	Phagophore Assembly Site Cytoplasm Mitochondrial Outer Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Membrane Axon Guanyl-nucleotide Exchange Factor Complex Phagophore Assembly Site Membrane Recycling Endosome Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane Extrinsic Component Of Autophagosome Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Rab GTPase Binding Identical Protein Binding Protein-containing Complex Binding GTPase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Protein Exit From Endoplasmic Reticulum Aggrephagy Autophagosome Maturation	Autophagosome Assembly Protein Phosphorylation Autophagy Signal Transduction Protein Localization Regulation Of Autophagy Positive Regulation Of Autophagy Macroautophagy Regulation Of Macroautophagy Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Neuron Projection Regeneration Neuron Projection Development Negative Regulation Of Protein Complex Assembly Cellular Response To Nutrient Levels Response To Starvation Protein Autophosphorylation Axon Extension Autophagy Of Host Cells Involved In Interaction With Symbiont Positive Regulation Of Autophagosome Assembly
Pathways		Macroautophagy	Macroautophagy TBC/RABGAPs RAB GEFs exchange GTP for GDP on RABs Receptor Mediated Mitophagy
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 28552196) Metabolite levels ( 23823483)	Body mass index ( 26426971) Mercury levels ( 26025379)
Interacting Genes		19 interacting genes: AMBRA1 ANK2 ANK3 ATG13 ATG4B CUL3 KBTBD6 KBTBD7 LMNB1 MEFV NEDD4 OPTN RB1CC1 SQSTM1 TAX1BP1 TRIM21 ULK1 WDFY3 WDR81	23 interacting genes: ATG13 ATG9A BECN1 EXOC8 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C MAPK14 MBP MEFV MUL1 NEDD4L OCLN PPP1CA PRKAA1 SDCBP SMCR8 SYNGAP1 UBC USP20
Entrez ID		440738	8408
HPRD ID		14226	11933
Ensembl ID		ENSG00000197769	ENSG00000177169
Uniprot IDs		Q9BXW4	O75385
PDB IDs		2NCN 3VVW 3WAM 3WAP 5DPW	4WNO 4WNP 5CI7 6HYO 6MNH 6QAS
Enriched GO Terms of Interacting Partners?
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