KPNA3 and HNRNPC

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		KPNA3	HNRNPC
Description		karyopherin subunit alpha 3	heterogeneous nuclear ribonucleoprotein C
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol Host Cell	Nuclear Chromatin Extracellular Region Nucleus Nucleoplasm Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Actin Cytoskeleton Membrane Protein-containing Complex Extracellular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Telomerase RNA Binding N6-methyladenosine-containing RNA Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing RNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways	SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Triiodothyronine/thyroxine ratio ( 30824882)	Bipolar disorder ( 31043756 21738484) Height ( 31562340)
Interacting Genes		33 interacting genes: APOL6 ARNT CDKN1B COIL DDX21 EPAS1 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 GTF2IRD1 HIF1A HNRNPC HSPB1 KPNB1 MAT2B MVP MYOD1 NFE2L2 NFKB1 NUP50 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131	51 interacting genes: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CELF1 CSNK1A1 CSNK2A1 CSNK2A2 DHX9 EPS8 ERG ESR1 FAS FXR2 GRB2 IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KRAS LMO2 LMO3 PALB2 PDGFB PHKB PIN1 PJA1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 TRAF3 UBE2I YWHAE YWHAQ ZFYVE26 ZNF581
Entrez ID		3839	3183
HPRD ID		03536	01243
Ensembl ID		ENSG00000102753	ENSG00000092199
Uniprot IDs		A0A024RDV7 O00505	P07910
PDB IDs			1TXP 1WF2 2MXY 2MZ1 3LN4
Enriched GO Terms of Interacting Partners?
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