KPNA3 and RCC1

Number of citations of the paper that reports this interaction (PubMedID 10744690)
26

Data Source:
HPRD (in vitro)

		KPNA3	RCC1
Description		karyopherin subunit alpha 3	regulator of chromosome condensation 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol Host Cell	Chromatin Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane Protein-containing Complex
	Molecular Function	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Chromatin Binding Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding Ran GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Regulation Of Mitotic Nuclear Division Viral Process Ran Protein Signal Transduction Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways	Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Triiodothyronine/thyroxine ratio ( 30824882)	Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		33 interacting genes: APOL6 ARNT CDKN1B COIL DDX21 EPAS1 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 GTF2IRD1 HIF1A HNRNPC HSPB1 KPNB1 MAT2B MVP MYOD1 NFE2L2 NFKB1 NUP50 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131	49 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 KPNA4 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 TLE1 TP53 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		3839	1104
HPRD ID		03536	01559
Ensembl ID		ENSG00000102753	ENSG00000180198
Uniprot IDs		A0A024RDV7 O00505	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs			1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB
Enriched GO Terms of Interacting Partners?
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